dba

 

Newsletter Jan, 2021

What We
Do with
Emerging
SARS-CoV-2
Variants

Multiple SARS-CoV-2 variants are circulating globally. Several new variants emerged in the fall of 2020, most notably:

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In the United Kingdom (UK), a new variant of SARS-CoV-2 (known as 20I/501Y.V1, VOC 202012/01, or B.1.1.7) emerged with an unusually large number of mutations.

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In South Africa, variant known as 20H/501Y.V2 or B.1.351 emerged independently of B.1.1.7. View More

Creative Diagnostics has produced a collection of recombinant antigens to evaluate the efficacy of the antibodies and vaccination for these variants.

Cat. No.

Product Name

Source

Additional Information

DAGC488

Recombinant SARS-CoV-2 Spike S1 (HV69-70/Y144 Deletion, N501Y, A570D, D614G, P681H) Protein [His]

HEK293 cells

Recombinant

DAGC489

Recombinant SARS-CoV-2 Spike S1(K417N, E484K, N501Y, D614G) Protein [His]

HEK293 cells

Recombinant

Our team has been keeping close attention to these?new variants and?is working diligently to develop a serial of Lentiviral SARS-CoV-2 Mutation Pseudovirus.

Lentiviral SARS-CoV-2 Mutation Pseudovirus

Lentiviral SARS-CoV-2 Mutation Pseudovirus

Cat. No.

Product Name

Reporter Gene

COVL-B117

Pseudotyped Luciferase rSARS-CoV-2 Spike (Variant B.1.1.7)

Luciferase

COVG-B117

Pseudotyped GFP rSARS-CoV-2 Spike (Variant B.1.1.7)

GFP

COVL-N439K

Pseudotyped Luciferase rSARS-CoV-2 Spike (N439K)

Luciferase

COVG-N439K

Pseudotyped GFP rSARS-CoV-2 Spike (N439K)

GFP

COVL-501YV2

Pseudotyped Luciferase rSARS-CoV-2 Spike (Variant 501Y.V2)

Luciferase

COVG-501YV2

Pseudotyped GFP rSARS-CoV-2 Spike (Variant 501Y.V2)

GFP

CD anti-nucleoprotein antibodies are expected to detect both UK and South African variants of SARS-CoV-2.

SARS-CoV-2 Nucleoprotein Antibody Pairs for Rapid COVID-19 Antigen Assays

SARS-CoV-2 Nucleoprotein Antibody Pairs for Rapid COVID-19 Antigen Assays

Cat. No.

Product Name

Source

Application

CABT-MMB1

Mouse Anti-SARS-CoV-2 NP monoclonal antibody, clone NB1

Mouse

Capture

CABT-MMB2

Mouse Anti-SARS-CoV-2 NP monoclonal antibody, clone NB2

Mouse

Capture

CABT-RMJ1

Rabbit Anti-SARS-CoV-2 NP monoclonal antibody, clone NJ1

Rabbit

Detection

Best pairs in lateral flow: If you are developing a lateral flow-based test, we recommend starting with these two capture-detection pairs: CABT-MMB1-CABT-RMJ1, and CABT-MMB1-CABT-MMB2.

New MAbs Available

New MAbs Available

We are pleased to let you know that we now have the first anti-nucleoprotein antibody (CABT-MMT2) that can not react with the B.1.1.7 variant strain but react with other COVD-19 viral strains.

This antibody can be used for COVID-19 antigen lateral flow testing in differentiating Variant B.1.1.7 and other viral strains.

We remain focused on our mission to serve life scientists to achieve their mission, faster. We know that many scientists are still diligently pursuing their research, and we'll continue to support our customers and partners worldwide.

COVID-19 Research

Isolated Super Potent Antibody Cocktail Can Defend Against SARS-CoV-2 Attack

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) appeared at the end of 2019, and the sequencing was completed in January 2020... Learn more

Neuropilin-1 Promotes SARS-CoV-2 Entry into Host Cells

The 2019 Coronavirus Disease (COVID-19) caused by the new coronavirus SARS-CoV-2 is now raging around the world. Existing studies have shown that SARS-CoV-2 infects host cells through the receptor ACE2... Learn more


 

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