Type III collagen is vital for the formation of normal type I collagen fibrils in the cardiovascular system, intestines, and skin. In the extracellular matrix (ECM),
type III collagen is a major component of the interstitial matrix. It is secreted by fibroblasts and other mesenchymal cell types, playing roles
in various inflammation-associated pathologies such as lung injury, viral and nonviral liver diseases, kidney fibrosis, hernia and vascular disorders.
Reliable isolation of type III collagen is critical for researchers working with precious samples
Chondrex introduces a type III collagen isolation and analysis protocol using a modified PAGE system with urea, which separates type I and III collagen in a gel.
Easy to perform and applicable to small amounts of sample, this method can be quickly integrated to improve current workflows.
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