Vector Laboratories was founded in 1976 and has been a trusted partner to the global scientific community for nearly five decades.
Starting with immunohistochemistry, Vector grown into a leader in labelling, detection and conjugating technologies for fields like cancer research,
neuroscience, immunology and infectious disease.
ImmPRESS® Polymer Reagents for IHC
Integrated antibody and enzyme technology for high-sensitivity IHC detection
Polymer-based reagents are a more recent introduction into IHC detection methodology than traditional avidin and biotin conjugates, such as ABC kit formats. Polymers offer distinct advantages over these traditional methods particularly for applications such as multiple antigen labelling (multiplexing)
on the same tissue section, or in instances where detectable levels of endogenous biotin may be problematic.
Polymer-based systems essentially consist of an integrated polymer of active enzyme and secondary antibody that binds to a primary antibody target.
This integrated format introduces significantly more enzyme at the site of localization, thereby generating a greater reaction with the subsequent chromogen,
as compared to the use of a secondary antibody directly conjugated with enzyme.
Additionally, use of a one-step polymer method shortens the IHC procedure by avoiding the two-step biotinylated secondary antibody
and ABC reagent step that is required for standard avidin-biotin systems.
ImmPRESS Polymer Detection Kits require little optimization and facilitate quick, efficient detection in cell- and tissue-based applications.
These kits offer:
High sensitivity for optimum immunohistochemistry detection
Unique, non-biotin based micropolymer technology
Ready-to-use, pre-diluted reagents
Time-saving one-step protocols
Choice of enzyme (HRP or AP)
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